Fibrotic scars may contain slowly multiplying tubercle bacilli with the potential for future progression to active tuberculosis.
2.
Collapse inhibited the proliferation of tubercle bacilli and stimulated the formation of scar tissue that controlled the disease.
3.
Artificial pneumothorax, for example, involved collapsing a diseased lung, which inhibited growth of tubercle bacilli.
4.
Tubercle bacilli, either free or within phagocytes, drain to the regional nodes, which also often caseate.
5.
In too many cases the patient spits on the floor of churches and meeting-houses, scattering the tubercle bacilli all round.
6.
Koch announced a glycerine extract of the tubercle bacilli as a " remedy " for tuberculosis in 1890, calling it " tuberculin ".
7.
In 1925, Treat Baldwin Johnson and Coghill were detected a minor amount of a methylated cytosine derivative as a product of hydrolysis of tuberculinic acid, from avian tubercle bacilli, with sulfuric acid.
8.
This extraction method led to Georges Dreyer s diaplyte and Dreyer's synthetic medium for the growth of tubercle bacilli; Dreyer's advances lead to a more effective form of tuberculin skin test.
9.
According to J . S . Faulds, Zaidi and coworkers " produced the nearest approach to massive fibrosis by injecting into sensitized animals dust plus tubercle bacilli ", importantly, as tuberculosis was prevalent at the time.
10.
The essence of the method was the use of multiple drugs taken simultaneously to reduce the chance for drug-resistant strains of the tubercle bacilli to develop; this combined with careful monitoring of patients to ensure that they adhered to the prescribed medication regime.
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